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Genestra Methylation Support, 90 capsules Vitamin B6 Pyridoxine and P5P This condition can cause aGenestra Methylation Support Details Methylation Support provides a combination of betaine, choline, and B vitamins in their physiologically active form to help support homocysteine metabolism. Homocysteine is an amino acid that can be further metabolized into methionine or cysteine, and normal homocysteine levels are necessary for the methylation of nucleic acids, proteins and lipids, as well as protein production. A randomized, double blind trial